The article is devoted to the consideration of the ontological meaning of the concept of «value relation» in the process of cognition. The scientific novelty of the research consists in substantiating the methodology of a holistic consideration of the problem of the role and place of the value relation in the system of bases of scientific cognition. This methodology assumes the consideration of social, historical and epistemological factors and allows us to consider the development of science in connection with the values of the dominant scientific paradigm.
