Izvestiya of Saratov University.
ISSN 1819-7671 (Print)
ISSN 2542-1948 (Online)


clinical trials

The problem of eligibility criteria in biomedical experiment: Philosophical and methodological analysis

Introduction. The formation and development of modern evidence-based medicine is not possible without clinical studies with the participation of humans as subjects. The methodology of such experiments is based on careful selection of subjects based on the so-called eligibility criteria – parameters which form the optimal patient group for studying the therapeutic properties of a particular drug based on the science community’s expectations.

Phenomenon of a therapeutic misconception: Bioethical aspect

Introduction. The obligatory study of medical drugs during clinical trials conduction can be named as one of the fundamental principles of evidence-based medicine. The article deals with the phenomenon of a therapeutic misconception occurring in volunteers participating in such experiments, who failed to understand the scientific goals of clinical trials and incorrectly expect the therapeutical advantages linked with such a participation.